The 2023 Nobel Prize in Medicine has been granted to Katalin Karikó from Hungary and Drew Weissman from the United States. They are being recognized for their groundbreaking work related to the modification of nucleoside bases, which paved the way for the development of highly effective mRNA vaccines against COVID-19. Katalin Karikó serves as a professor at Hungary's Sagan University and holds an adjunct professorship at the University of Pennsylvania. Drew Weissman collaborated with Karikó on the research that led to this prestigious award while they were both affiliated with the University of Pennsylvania. These two scientists, who had been widely considered as frontrunners for the Nobel Prize, are being celebrated for their crucial contributions in the field of nucleoside base modifications. Their discoveries played a pivotal role in the rapid development of mRNA vaccines during one of the most significant global health crises in recent history. The Nobel laureates' work not only accelerated vaccine development but also contributed to addressing one of the greatest threats to human health in modern times. Their dedication and innovation have led to the unprecedented speed at which effective vaccines were developed. The Nobel Prize recipients will receive their accolades, including a diploma, a gold medal, and a $1 million monetary award, during a formal ceremony in Stockholm on December 10th. This date marks the anniversary of the 1896 passing of Alfred Nobel, the scientist who established the Nobel Prizes in his last will and testament. In accordance with Nobel's wishes, laureates of the peace prize will be honored in Oslo, while the ceremony for the other Nobel Prizes will take place in Stockholm. The Nobel Prize in Medicine serves as the opening act for this year's Nobel Awards, with five more categories set to be announced in the days to come. These prestigious awards, initiated in 1901 by Swedish inventor and affluent entrepreneur Alfred Nobel, recognize outstanding accomplishments in the fields of science, literature, peace, and, in later years, economics. UN Chief Guterres Reflects on Gandhi's Legacy and the Power of Non-Violence