Canadian Experts studying effectiveness, safety of COVID vaccines during pregnancy

The Government of Canada, through its COVID-19 Immunity Task Force (CITF) and Vaccine Surveillance Reference Group (VSRG), is investing USD 1.3 million approx for two Canadian research teams to further evaluate vaccine safety and effectiveness in pregnant people.

While pregnant or breastfeeding individuals were excluded from the initial mRNA and viral vector COVID-19 clinical trials, recent real-world evidence is showing that mRNA COVID-19 vaccines are safe during pregnancy. Additional research and surveillance of COVID-19 vaccination among pregnant and lactating populations is needed.

The results will be communicated regularly to public health officials to help inform decision making for the ongoing Covid-19 vaccine administration programme.Researchers from the University of British Columbia, leading the first study called COVERED, are launching a Covid-19 vaccine registry for pregnant and breastfeeding people across Canada.

"We are asking pregnant and breastfeeding individuals in all 10 provinces and three territories to sign-up for the registry, after which they will be invited to fill out a survey," said study lead researcher Deborah Money, Professor at the varsity's Department of Obstetrics and Gynaecology.

The second study will link information collected from the Better Outcomes Registry and Network (BORN) Ontario Registry, which collects data from every baby born in Ontario, with the province's vaccination registry from the Ontario Ministry of Health (COVaxON).

Researchers will monitor the health outcomes and effect of vaccines on mothers and their babies, comparing individuals who received a Covid-19 vaccine during pregnancy, or just before, with those who did not. The findings from this study will help to fully inform pregnant people, their care providers, and public health policymakers.

 

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