The development of new drugs is one of the major challenges in the medical field, given the increasing resistance of bacteria to medicines worldwide. The manufacture of new antibiotics is usually based on natural products such as plant extracts and fungi, or a series of chemicals stored in the chemical library. However, in research work involving the discovery of antibiotics, the importance of such procedures is often increased, with relatively little research. Therefore, the development of 'quinonapoxide' as a new antibiotic agent is considered important.

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According to media reports, Indian scientists have identified proteins in the form of staphylococcus aureus form resistant to antibiotics against bacteria that can be targeted at the molecular level to destroy the bacteria. Scientists say that based on this discovery, it may help to develop new antibiotics.

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In its statement, the researchers have also developed a molecule during this study that can destroy the bacteria by targeting the MAR-R protein identified in the bacteria. This molecule is an indole-based quinone epoxide, which acts as an active antibacterial agent. Quinone epoxide kills bacteria by penetrating the cells and disrupting the functioning of MAR-R proteins in them. , Jointly by scientists from Lucknow and Indian Institute of Science Education and Research (IISER), Pune Yyn research journal has been published in Medicinal Chemistry.

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