World Alzheimer's Day, medical professionals expressed alarm about the rising obesity rate and its link to dementia cases.

It is well-known that obesity is the root cause of all diseases, and that obesity in middle age is a recognised risk factor for Alzheimer's. "The health of the brain is significantly impacted by being overweight or obese, particularly in the areas most susceptible to the impacts of Alzheimer's disease. Possibly making the symptoms of Alzheimer's disease worse if it ever materialises "KIMS Hospitals consultant neurologist Dr. Haritha Koganti.

The doctor stated that research has shown that in overweight or obese individuals without severe cognitive impairment, the more excess weight they carry, the larger the levels of brain cell loss and the lower the cerebral blood flow.

Dr. Manoj Vasireddy, Consultant Neurologist, Amor Hospitals claims that the absence of regular physical activity has an effect on brain processes and may eventually cause it to work less well. "Dementia may result from brain function deterioration, which is a severe problem. Alzheimer's disease is on the rise in our culture as a result of obesity among middle-aged people, which is a big issue," he said.

"Leptin and insulin resistance are known to increase in association with obesity. Adipose tissue produces the peptide hormone leptin, which primarily controls food intake. Leptin reduces the release of insulin and increases tissue sensitivity to it through negative feedback, which causes glucose uptake for use as fuel or storage as well as chronic low-grade inflammation in the blood vessels of various organs, including the brain "SLG Hospitals consultant general physician Dr. Gowri Shankar Bapanapalli said.

Dr. Suresh Reddy, a consultant in neurology at Aware Gleneagles Global Hospital, claims that being overweight or obese over the course of a person's lifetime reduces the brain's resistance to the illness's harmful consequences. Therefore, it is crucial that each person maintain an active physical lifestyle, which would guarantee that their brain obtains enough nutrition to support healthy functioning. He noted that since there is now no known cure for Alzheimer's disease, it is crucial to start taking preventive measures as early as possible.

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