India's fight against the coronavirus is going to get stronger as the country will be releasing the first batch of the anti-COVID-19 drug 2-deoxy-D-glucose (2-DG) today (May 17, 2021). It will be released by Defence Minister Rajnath Singh.
Over 10,000 doses of the 2-DG drug, are likely to be launched today.
The 2-DG drug has been developed by DRDO's Institute of Nuclear Medicine and Allied Sciences (INMAS) in collaboration with Dr Reddy`s Laboratories.
The drug reportedly comes in powder form and is taken orally by dissolving it in water.
In April 2020, during the first wave of coronavirus, INMAS-DRDO scientists conducted laboratory experiments with the help of the Centre for Cellular and Molecular Biology (CCMB), Hyderabad and found that this molecule works effectively against the SARS-CoV-2 virus and inhibits viral growth. Based on these results, DCGI CDSCO permitted a Phase-II clinical trial of 2-DG in COVID-19 patients in May 2020.
The DRDO, along with its industry partner DRL started clinical trials to test the safety and efficacy of the drug in COVID-19 patients. In Phase-II trials (including dose-ranging) conducted from May to October 2020, the drug was found to be safe in COVID-19 patients and showed significant improvement in their recovery. Phase IIa was conducted in six hospitals and Phase IIb (dose-ranging) clinical trial was conducted at 11 hospitals all over the country. Phase-II trial was conducted on 110 patients.
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