In a cohort study, researchers from the University of Padua and Imperial College London tested over 85 percent of the 3,000 residents of Vo’, Italy, in February/March 2020 for infection with SARS-CoV-2, the virus that causes COVID-19, and tested them again in May and November 2020 for antibodies against the virus. The Researchers discovered that Antibody levels remain high nine months after infection from SARS-CoV-2, the virus that causes Covid-19, whether symptomatic or asymptomatic.

The team found that 98.8 percent of people infected in February/March showed detectable levels of antibodies in November, and there was no difference between people who had suffered symptoms of Covid-19 and those that had been symptom-free. The results are published in the journal Nature Communications. Further, while all antibody types showed some decline between May and November, the rate of decay was different, depending on the test to track the antibody levels.The team also found cases of antibody levels increasing in some people, suggesting potential re-infections with the virus, providing a boost to the immune system.

"We found no evidence that antibody levels between symptomatic and asymptomatic infections differ significantly, suggesting that the strength of the immune response does not depend on the symptoms and the severity of the infection," said lead author Ilaria Dorigatti, from the MRC Centre for Global Infectious Disease Analysis at Imperial.

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