Study Reveals: Pfizer, Moderna Vaccines Likely Induce 'Persistent’ Immunity to COVID

A study results indicates that Vaccines from Pfizer and Moderna mount a "persistent" immune response to COVID-19. The paper published Monday in the journal Nature, adds to a growing body of evidence that the protection from the virus-induced by the vaccines could be long-lasting. It may mean that booster shots for the mRNA coronavirus vaccines aren't needed anytime soon.

Researchers found that the so-called germinal centers in participants' lymph nodes were highly active nearly four months after the first dose of vaccine, suggesting that fully vaccinated people could have long-term protection.

"This is evidence of a really robust immune response," said co-senior author Rachel Presti, associate professor of medicine. "Your immune system uses germinal centres to perfect the antibodies so they can bind well and last as long as possible. The antibodies in the blood are the end result of the process, but the germinal centre is where it is happening."

The researchers extracted cells from 14 people who received the Pfizer vaccine. Samples were obtained three weeks after the first dose, and at weeks four, five and seven. Ten of the participants gave additional samples 15 weeks after the first dose. None of the participants previously had been infected with the virus that causes Covid-19, as per reports.


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