A new study conducted in  Italy has identified a dose-response relationship between the concentration of everyday pollutants and the incidence of out-of-hospital cardiac arrest. The research is presented at ESC Congress 2021.

The findings of the research were presented at ESC Congress 2021. "We studied seven common pollutants and found that as the concentration of each rose, the risk of cardiac arrest increased," said study author Dr. Francesca R. Gentile of the IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

"The findings suggest that air quality should be incorporated into predictive models to assist health systems in planning service requirements," added Dr Gentile. Air pollution has been established as a potential trigger for out-of-hospital cardiac arrest but the relationship with specific air pollutants remains controversial because of the number of mechanisms involved. This study examined the associations between short-term exposure to particulate and gaseous pollutants and the incidence of out-of-hospital cardiac arrest.

The study was conducted in the provinces of Pavia, Lodi, Cremona and Mantua in southern Lombardy, which cover 7,863 km2 across metropolitan and rural areas with more than 1.5 million inhabitants. Data on the daily incidence of cardiac arrest in 2019 were obtained from the regional cardiac arrest registry Lombardia CARe. Information on daily concentrations of particulate matter (PM10, PM2.5), nitrogen dioxide, carbon monoxide, benzene, sulphur dioxide and ozone across the study territory were provided by the regional agency for environmental protection (ARPA).

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