NEW YORK: According to a new study, mRNA booster immunisations extend protection against moderate and severe Covid-19 for four to five months before their efficacy begins to decline.

The research, which was published in The BMJ, revealed that the Omicron period mRNA vaccine's initial, strong (89%) protection against severe Covid-19 declined following primary immunisation.

Indiana University researcher Brian Dixon said, "in our new study, we looked at tens of thousands of patients in multiple states, seen over a year and a half." "Our research offers solid evidence of the efficacy of boosting to raise immunity, as well as the fact that this immunity tends to diminish after four to five months, indicating the need for additional booster doses," Dixon said.

The US researchers from January 17, 2021, to July 12, 2022 examined data from patients seen at 261 hospitals, 272 emergency rooms, and 119 urgent care centres. The information included pre-Delta and pre-Omicron dominance periods as well acenterson dominance periods (including subvariants BA.4 and BA.5).

The study, which concentrated on the longevity of boosters against hospitalisation, found that effectiveness increased noticeably following a booster shot before declining again roughly four to five months later.
A second booster led to an increase in protection once more. With Moderna and Pfizer boosters, the protection and fading patterns were comparable.

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