Scientists of Vanderbilt University USA have invented a three-dimensional (3D) organ-on-a-chip that can do an impersonation of heart's biochemical properties and that will be very helpful in studying cardiac disease, framing, and development of drugs. 

Professor John Wikswo, one of the inventor said, “We created the I-Wire Heart-on-a-Chip so that we can understand why cardiac cells behave the way they do by asking the cells questions, instead of just watching them. We believe it could prove invaluable in studying cardiac diseases, drug screening and drug development, and, in the future, in personalized medicine by identifying the cells taken from patients that can be used to patch damaged hearts effectively.”

This device has some unique aspects, which represents about two millions of a human heart, it controls the mechanical force applied to cardiac cells. This allows the researchers to reproduce the mechanical conditions of the living heart, which is continually stretching and contracting, in addition to it, the electrical and biochemical environment are also manipulated.

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