An explosion at an industrial park for chemical companies shook the German city of Leverkusen on Tuesday, sending a large black cloud rising into the air. Several people were injured, and five were missing. The Federal Office for Civil Protection and Disaster Assistance classified the explosion as “an extreme threat” and asked residents to stay inside and keep windows and doors closed, German news agency dpa reported. Operators of the Chempark site in Leverkusen, about 13 miles north of Cologne on the Rhine river, said the cause of the explosion was unclear. Currenta, the company that operates the chemical park, said in a statement that several employees were injured, at least two of them severely. Police in Cologne said they did not have any information on the cause or size of the explosion, but a large number of police, firefighters, helicopters and ambulances were deployed to the scene. They asked all residents to stay inside and warned people outside Leverkusen to avoid the region. The explosion took place in the Buerrig neighborhood at a garbage incineration plant of the chemical park, smoke cloud moved northwest toward the towns of Burscheid and Leichlingen. Firefighters from all over the region were called in to help extinguish the fire. This disease takes a life of life every 30 seconds, It's very important to build awareness White House announces Covid-19 vaccination mandatory for all federal workers Germany: 5 People gone Missing After Explosion Rocks German Chemicals Site UNESCO names Harappan city of Dholavira as world heritage site