Thalassemia is a genetic blood disorder that is passed down from parents to children. It is a type of blood disorder that affects the production of hemoglobin, a protein in red blood cells that carries oxygen to different parts of the body. If left untreated, thalassemia can lead to severe health complications and even death.
According to the World Health Organization (WHO), India sees 7-10,000 thalassemia-affected births every year, with 1,500 of them being in Delhi and its surrounding areas. The disease affects 3.4% of the total population, making it a significant health concern.
Thalassemia is caused by a defect in the production of hemoglobin, which is made up of two proteins - alpha globin and beta globin. The defect leads to rapid destruction of red blood cells, resulting in a severe shortage of blood in the body. This can lead to anemia, weakness, and shortness of breath.
There are two types of thalassemia - major and minor. Thalassemia major is a more severe form of the disease that occurs when both parents are carriers of the defective gene. Thalassemia minor, on the other hand, is a milder form of the disease that occurs when only one parent is a carrier.
Symptoms of thalassemia include pale skin, yellowing of the nails and tongue, jaundice, and enlarged liver and spleen. Children with thalassemia may also experience stunted growth, weakness, and frequent infections.
It is essential for couples to undergo blood tests before marriage to detect the presence of thalassemia. If both parents are carriers of the defective gene, there is a 25% chance of their child inheriting the disease.
Untreated thalassemia can lead to severe health complications, including heart problems, liver and kidney damage, and even death. Blood transfusions can help manage the disease, but they can also lead to iron accumulation in the body, which can be harmful to the heart, liver, and lungs.
In conclusion, thalassemia is a genetic blood disorder that can have severe consequences if left untreated. It is crucial for couples to undergo blood tests before marriage and for parents to get their children tested for thalassemia at an early age. With proper treatment and management, it is possible to lead a normal life with thalassemia.
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