World Day for Laboratory Animals was instituted in 1979 and has been a catalyst for the movement to end the suffering of animals in laboratories around the world and their replacement with advanced scientific non-animal techniques.  The suffering of millions of animals all over the world is commemorated on every continent. Although advanced methods are steadily replacing animal research, outdated laws require animal tests before a product can be put on the market. Every year millions of animals suffer and die in experiments that can never be trusted.

the event is marked by demonstrations and protests by groups opposed to the use of animals in research.In April 2010 protesters marched through central London calling for an end to the use of animals in research,.[5] A similar march took place in Birmingham in 2012.and Nottingham in 2014.

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World Day and World Week For Animals In Laboratories have also attracted attention from scientific groups defending the use of animals in research. On 22 April 2009 members of UCLA Pro-Test held a rally in support of biomedical research on animals,[8] and to condemn the violence and harassment directed at faculty member Prof. David Jentsch by animal activists. NAVS and other groups opposed to animal research have claimed that World Day For Animals In Laboratories is recognised by the United Nations. However, the day is not included on the official list of United Nations observances.

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